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u/photoboi ยท 1 pointr/askscience

Interesting - I was reading about this just today

Fever production has a postive effect on the course of infection. However, for every 1 degree celsius rise in temperature, there is a 13% increase in resting metabolic rate and oxygen consumption. Fever therefore leads to increased energy requirements at a time when anorexia (caused by the release of cytokines in the body's immunological response to pathogens - bacteria or virus') leads to decreased food intake. The normal compensatory mechanisms in starvation (e.g mobilization of fat stores) are inhibited in acute infections. this leads to an increase in skeletal muscle break-down releasing amino-acids, which, via gluconeogensis are used to provide energy.

Source (page 87)