Reddit reviews Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

Ending Aging

In case people are interested in learning more:

SENS Web site

De Grey's book, "Ending Aging", which I've read and he lays it out quite nicely for non-scientists.

The Second Machine Age, by McAfee and Brynjolfsson.

The Zero Marginal Cost Society by Rifkin.

Ending Aging by De Grey.

Although I would personally argue that you get a good understanding of their material from the numerous talks they give, and learning the background science is probably more important for assessing their claims than simply reading their books.

A couple of years ago, in a talk, Aubrey waved two big books when the topic came up about how to get started. The books were:

• Essential Cell Biology
  
• Molecular Biology of the Cell
  
  (and SENS would most likely also recommend keeping Ending Aging handy).

If you want a lot of detail, Ending Aging is a great book about them.

For junk inside cells, we just have to add enzymes to lysosomes that can break down the stuff that accumulates there.

For mitochondria, adding their DNA to the nucleus would eliminate the problem of cells that end up in a state where they're dominated by mitochondria that don't work.

For the crap between cells, the immune system is best placed to clean it up for us. We have to inoculate against what we don't want.

For the weakening immune system, the biggest thing is to be able to grow people a new thymus either with stem cells or the kind of scaffolding techniques that have been used recently to grow people a new trachea or a new blood vessel.

Stem cells of various types are the likely answer to most cases where we're losing cells faster than they're replaced.

It's a pretty exciting time for medicine.

Phoenix has gone but I'll attempt to field this with my own answers:

1. Whenever we actually have something like Freitas' nanomedicine, and that will only come online once we have real APM. From my limited perspective 2030 looks like a reasonable date to expect effective but primitive APM created microbivores and pharmocytes. I'm assuming that APM will be reached by moving from a DNA origami basis.
   
   
2. Yes. As Drexler talked about back in 1986 with EoC nanoscopic robots that could start and stop metabolism could bring on true biostasis and the conquest of death.
   
   
3. Completely ignore them. The corporations will attempt to use the very state that they partner with for mutual defense in order to suppress competition. A rejection of both entities and widespread encrypted communications containing the plans for creating these bits of nanomedicine is probably the only way around until a new society is strong enough to defend itself from the death throes of the old.
   
   
4. Whatever aging actually is, it's a process that affects us physically. Nanotechnology (or APM) is essentially mastery of the material universe, of which human bodies are a part. By making, breaking, preserving, or preventing chemical bonds essentially anything not expressly prohibited by physical law can be done. This includes reversing aging.
   
   
5. You'd likely be able to look however you want to look. It'll probably be freaky to have a talking newborn though. I think some of this is covered in Aubrey de Grey's "Ending Aging".
   
   
6. Yes, and I think he hits the mark pretty much everywhere. But he usually does.

Ending Aging would be probably good for bodily autonomy. Check out Aubrey de Grey's book too.

Besides the already mentioned site and its associated standard work here, [this book](http://www.goodreads.com/book/show/178788.The_China_Stu dy) also contains lots of sources. This book is useful too. It isn't about vegan diets but it discusses every aspect of aging and nearly all are made worse by animal based diets.

Google scholar is also an amazing way to quickly find the latest scientific information on just about anything. Another amazing tool is sci-hub.cc and /r/Scholar for finding articles. Whole books can easily be found on gen.lib.rus.ec the current location of Library Genesis which contains millions of scientific textbooks.

It's not inevitable. Here you go:

Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

Transcend: Nine Steps to Living Well Forever

The Singularity Is Near: When Humans Transcend Biology

On the "you're seen as crazy if you seriously consider X" topic, I was going to ask about Grey's opinion on cryonics. However, after googling, it turns out they already talked about it around a year ago (link, it's around 10 minutes long), and I had just forgotten. Upon re-listening, I can even remember 2016-me being frustrated that Brady's objection was very uncommon, so most people listening with objections wouldn't have their point addressed.

For more information about cryonics, I'd recommend Tim Urban's Wait But Why article, Why Cryonics Makes Sense.

For more information about an end to aging, I'd recommend the first few chapters of Aubrey de Grey's Ending Aging.