Reddit Reddit reviews Metabolic Regulation: A Human Perspective

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Metabolic Regulation: A Human Perspective
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1 Reddit comment about Metabolic Regulation: A Human Perspective:

u/[deleted] ยท 2 pointsr/leangains

my knowledge of this is self taught and not formal education, so take it with a block of salt. this is the book I mainly learnt from.

http://www.amazon.com/Metabolic-Regulation-Perspective-Keith-Frayn/dp/063206384X

>Nitpicking is sincerely appreciated. I know it won't deplete glycogen totally, just find it interesting as a possible mechanism.

-glycogen phosphorylase liberates stored glycogen (~100g liver, ~400g muscles: the latter amount is higher in people with, uh, more muscle)-liver can release into bloodstream (after a 12 hr fast or so it'll be reduced somewhat, mostly for brain fuel), but muscle glycogen cannot be re-released into the bloodstream, fasted or not
-under fasted conditions, increased catecholamines increases cAMP and then as a result, glycogen phosphorylase is increased as well (BUT muscle glycogen cannot really deplete without exercise, at all)

>Is it an off-on thing? Does it need to be all depleted or no super-compensatory effects will be established?

-supercompensation, as opposed to just regular compensation, only occurs in muscles that were exercised and depleted. So for our purposes, there wouldn't be any supercompensation (just regular)
-I am not sure if its an on/off thing, but I think depletion has to be done to a pretty high level (<-UD 2.0 requires 2 days of depletion, so I think its a strong requirement)

I haven't read it in a while, but lyle mcdonald's ud 2.0 discusses these topics in much better and educated detail. Some authors who wrote papers about this are Prevost, Alborg (sp?), Costil (don't have exact ones, on work computer right now)