Reddit reviews Take a Paddle: Western New York Quiet Water for Canoes & Kayaks

Yea as others have mentioned I run the Kayak Shack at Canalside and do tours so can give you some suggestions.

Buffalo River - Lots of put-ins along the way, starting from West Seneca there is the DEC Launch on Harlem near Mineral Springs, Seneca Bluffs, Foot of Bailey, Red Jacket park, Riverfront Mutual park, Riverfest Park

On the Lake you can use the old sea plane launch near Lasalle park, which i don't think is an official launch but I know people that do use it.

Gallagher Beach is another decent place within city limits to launch from, as well as a few new launches on the Outer harbor that are being constructed as we speak so I can give more details.

Going South you have assorted Beaches to launch from for Lake paddling

North has more choices like Beaver Island on Grand Island and you can paddle to Strawberry island if you aren't weak, no offense but this area has more current than most, this feeds the Niagara falls so..be careful!

I know some go on Scajaquada Creek but I hear it smells bad and not sure where to launch from.

Still more North you have Ellicott Creek and Tonawanda Creek, this was used as the Erie Canal so can take you to Albany if you have time.

Beyond that i would check out this Local paddle Book for more info as I usually focus on the Buffalo River, or paddle in other States all together.

added - BTW We rent kayaks and SUP boards under the Skyway at Canalside 9-6 everyday and we offer tours through the Grain Elevators and the 11:30 we walk around Silo City and I give a personal hike/tour/sneak peak of the Rock Gym.