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The fact that it's mentally taxing and time-consuming means that it's likely working exactly as intended!

CBT saved and changed my life when I was at my darkest about six years ago. I've gone through some CBT here and there since then, but a lot of the lessons I learned the first time around have stuck with me and have helped over the years. To my understanding, CBT at its core is ultimately about learning to identify, catch, and fix your distorted thinking as it's occurring. This can be quite uncomfortable and exhausting at times, but it's 100% worth it in the end.

Also, if you aren't clicking with your therapist, find a new one! If you don't click with them, try another. That's not to say that you haven't found a great one already - just don't get discouraged if you don't feel like you mesh well. That's just part of the process, and therapists truly want clients they think are the best for each other.

Finally, I would really encourage you to stick with it for at least 8 sessions. It's tough but it's worth it if you really need it! (Although, I firmly believe that anybody could benefit from CBT - even perfectly healthy people who don't have any mood disorders.)

If you're looking to learn more about CBT and maybe try out some therapy in conjunction with what you're doing with your counselor, I would highly recommend The Feeling Good Handbook. This book is all about working through CBT on your own and provides a ton of extremely helpful exercises and overall informs you very well on the whole process. Keep in mind it's best used in conjunction with an actual therapist, especially if you're going through an episode of particularly bad depression or anxiety.

Welp, this ended up being a lot longer than I expected - I guess that's because CBT is very important to me, scientifically proven to work very very well, and I'm super excited for you to begin your journey with it. Keep at it, friend! In any case, good luck with your endeavors, and feel free to ask if you have any other questions. :)

I would love to experiment with GHB.

The history of GHB is one that has always interested me. It was sold without problem as a nootropic in health food shops before being banned (unfairly in my mind) as a date rape drug by the Clinton administration. Obviously be sensible, as others have pointed out you don't want to become addicted.

For various reasons I would love to experiment with GHB.

• Is an antidepressant
  
  
• Is a nootropic
  
  
• Is a sleep aid
  
  
• Increases muscle mass
  
  Here is [a post] (https://redd.it/3b81l4) I made a couple of years ago. I'll clean it up, and add a few more comments if I am more functional tomorrow but I wanted to let you know I think GHB is well worth researching:
  
  –––
  I have suffered from insomnia all my life (either that or sleeping for 22 hours straight). It has had a major impact on my life. One interesting book I found on the subject is Insomniac
  by Gayle Greene, a professor of literature and women’s studies at Scripps College.
  
  
  >I can't work, I can't think, I can't connect with anyone anymore. . . . I mope through a day's work and haven't had a promotion in years. . . . It's like I'm being sucked dry, eaten away, swallowed up, coming unglued. . . . These are voices of a few of the tens of millions who suffer from chronic insomnia. In this revelatory book, Gayle Greene offers a uniquely comprehensive account of this devastating and little-understood condition. She has traveled the world in a quest for answers, interviewing neurologists, sleep researchers, doctors, psychotherapists, and insomniacs of all sorts. What comes of her extraordinary journey is an up-to-date account of what is known about insomnia, providing the information every insomniac needs to know to make intelligent choices among medications and therapies. Insomniac is at once a field guide through the hidden terrain inhabited by insomniacs and a book of consolations for anyone who has struggled with this affliction that has long been trivialized and neglected. – source (amazon.com)
  
   
  
  She also has a blog, www.sleepstarved.org containing information for the sleep-deprived.
  
  You can read an excerpt of the book [here] (http://well.blogs.nytimes.com/2008/03/21/the-wretched-life-of-the-insomniac/).
  
   
  
  In my younger years I had great deal of difficulty falling asleep. Now I fall asleep easily enough but wake at ridiculously early hours – this morning I was up at 2:30am. Anyone have any solutions?
  
   
  
  Edit: One interesting idea to come out of Greene's book was that if bipolar is a spectrum disorder, sleep disturbances may be on the tail end of the spectrum. As a child I drove my parents crazy staying awake at all hours. Now I rather fear that sleep deprivation is making me crazy : (
  
  Another mention Greene makes is of GHB, the only efficacious medication she found. It is purportedly also a potent antidepressant. I used to buy it over the counter to use as a sleep aid (I had no knowledge and no interest in using it recreationally) It was a godsend. Sadly now it is illegal (possibly Greene suggests to protect the lucrative sleep medication market) Used therapeutically, the drug was such a game-changer, in the past I toyed with the idea of a) learning to manufacture my own GHB from scratch or b) emigrating permanently to a country where GHB it is still legal. Has anyone else had any experience (non-recreational) with GHB.
  
   
  
  Edit 2: A review of GHB: The Natural Mood Enhancer
  by Ward Dean, M.D., et al.
  
  http://ceri.com/rev-ghb.htm
  
  From the review:
  
  >Many readers will be familiar with GHB (gamma-hydroxybutyrate) from articles previously published in Smart Drug News. Many readers may have read the book Better Sex Through Chemistry by John Morgenthaler and Dan Joy, which contained a large and comprehensive overview of the use of GHB as a prosexual compound. Given such exposure, a great many Smart Life News subscribers may be tempted to regard this new book on GHB as redundant. However, nothing could be further from the truth.
  >
  >The authors certainly cover all the pertinent nuts-and-bolts issues of GHB usage. They discuss numerous indications for GHB, including narcolepsy, depression and relaxation. They provide an in-depth review of the scientific literature on GHB’s use in treating drug and alcohol withdrawal and addiction. They also discuss GHB’s ability to stimulate human growth hormone (hGH). One application I found of particular interest is GHB’s use in women to facilitatate labor and childbirth. This use truly speaks to the truth about GHB’s safety.
  >
  >For the record, I have used GHB as a sleep aid and as a prosexual supplement. In both cases, I have found the substance to be effective and safe. After hundreds of doses, large and small, I’ve not a single complaint. I have personally compared notes on the use of GHB with dozens of people and have referred thousands to a variety of sources for the product.
  
  Edit 3: You can get a flavor of Gayle Greene's take on GHB using Google's search inside a book function. For some reason I can't link directly but if you click on the [top link a simple search provides] (
  http://www.google.com/search?q="Gayle+Greene"+GHB) they will take you there
  
  Edit 4: GHB: The First Authentic Antidepressant An article about GHB's use as an antidepressant.
  
  > GHB is a remarkable molecule because it can suppress depressive ideation and anxiety, sometimes within less than 30 minutes. It also seems to be immediately active on the most severe and treatment-resistant forms of depression. Because of such remarkable properties I jokingly used to call GHB "Or Potable", which means "drinkable gold" in French! Indeed a molecule which can block your depression and suicidal ideas, anxiety, etc, in such an efficient way is as precious as gold because it can save your life. GHB saved my own life many times when all other antidepressants failed. For years I suffered of depressive episodes which did not react to conventional "antidepressants". Why? Because, in fact, most antidepressants (an antidepressant is also called a thymoanaleptic, which is a molecule that stimulates mood) are not really "antidepressants" per se but thymoanaesthetics. A thymoanaesthetic is a molecule which anaesthetises emotions and which thus blunts feelings. For instance, if you give "antidepressants" to, say, two lovers together, you will notice that their love feelings towards one another become anesthesised, blunted. Clearly, a molecule which blunts rewarding emotions is definitely not an authentic antidepressant but rather a "mind Xylocaine" (xylocaine is an anesthesiser). A thymoanaesthetic takes away a part of your personality and makes you a bit similar to people suffering from negative schizophrenia. On the contrary if you administer gamma-hydroxybutyrate to a pair of lovers you will notice that it will enhance their love feelings because it stimulates sociability.

I would recommend a high quality Omega 3 supplement as most "standard American diets" have too much Omega 6s and too little Omega 3s. Look up Steve Ilardi on YouTube, he talks about a program called Therapeutic Lifestyle Changes for Depression that involves sun/bright light exposure, vitamin D supplementation, supplementation with Omega 3s, and fostering social connections. I would recommend his book/audiobook titled The Depression Cure (iffy title TBH) but if you watch the lecture posted above you'll get the gist of what he talks about in the book. I know that my attempt at incorporating the aforementioned changes has helped me with my day to day moods and overall wellbeing. I have also started supplementing SAM-E Examine.com and have noticed improvement in my energy and ability to focus (more than Adderall even, which surprised me).

I've also been (loosely) following an intermittent fasting eating schedule and find it's much easier when I'm limiting processed foods/sugars and choosing high protein/high fat meals. Some days when I fast I feel so much more alive and alert, it's really quite interesting and something I intend to experiment with further. There's lots of interesting research out there regarding intermittent fasting/"time-restricted eating" and diets like low carb/keto/elimination/carnivore and their effects on mental and physical health.

As others have mentioned, have your thyroid function checked (TSH), check for anemia (CBC with or without differential; a differential evaluates the levels of various white blood cells that may indicate an acute or chronic infection/disorder), vitamin D levels (kind of an expensive test FYI), testosterone levels if male (also likely pricey). Testing for other vitamin/mineral deficiencies could get pricey. Look into self-order labs through companies like Quest Diagnostics or Lab Corp, you may be able to find decent pricing vs going through a doctor/insurance.

Depression is quite a slog, just know that there is always a negative and a positive side to your day to day choices and try to make the choice that imparts positivity. Each positive choice builds upon each other and snowballs (just like negative choices can lead to negative trends/outcomes).

I wish you the best in your journey towards peace, good health and contentment!

you need to listen to the below comments , if you have this problem go see your doctor, is really important. But if you want to stop taking it then that is great but be sure to be controlled by your doctor. After that start working on yourself, you can cure this shit without any medical help, i would strongly recommend to you this book ''https://www.amazon.com/Body-Keeps-Score-Healing-Trauma/dp/0143127748 '' where you can find out why this is happening and how to stop it naturally. For me it was morning ritual, meditation, yoga, kickboxing, pushing yourself to the limit, have you meaning in what is happening . As well great book to anchor your day is Miracle Morning.

it depend on you if you want to take the easy way ( prozac) or the hard way ( working on yourself ) that will create character and life without depression

They did, however, that was a year and a half ago with no updates since, and it seemed more like a business move rather than anything else IMO. NSI failed to reach statistical significance in the primary endpoint, namely the clinician-rated scale MADRS. Earlier this year they also announced that they're expanding their pipeline. By all accounts, though they haven't explicitly stated so, it seems clear to me that they're not pushing it forward for MDD.

It's an interesting case, I was really hoping NSI would succeed as it seemed to have the potential to do, the self-rated scales don't lie, people actually felt better and stayed better until the last follow-up. Neuralstem made a good point about the MADRS and HAMD scale being 4-decade old scales designed primarily with tricyclics in mind, and they also do not capture atypical symptoms of MDD. It does seem a bit silly testing such a novel drug with ancient scales, and perhaps it would have succeeded otherwise.

I took it for about 2 weeks and it gave me severe neuropathic pain in my foot. I was almost limping around for a few days. You made a good point about these shady Chinese sources. On the other hand, most of the synthetic nootropics people are taking are synthesized in China.

I'm going into my 4th year of a Pharmacology degree, and I have been seriously thinking about going into mental health, precisely due to the reasons you stated. It's clear that our current understanding of depression is lackluster, and our treatments are really poor. I think there's so much potential for discovery and improvement in this field, and the movement has already started with the likes of esketamine, and the large number of new compounds currently in clinical trials (the article that I linked in my previous reply), many of which work through novel mechanisms.

Check out the highly influential study by Irving Kirsch in 2008: https://www.ncbi.nlm.nih.gov/pubmed/18303940/

This book is on my list as it seems to be a very comprehensive resource: https://www.amazon.com/New-Mind-Body-Science-Depression/dp/0393706664

Revitalising monoamine oxidase inhibitors: https://www.cambridge.org/core/journals/cns-spectrums/article/revitalizing-monoamine-oxidase-inhibitors-a-call-for-action/32497C0FE4F08D0D4C07E6350A91B0EE

Not the answer you're looking for, but I think I do, but I also can't confidently say probiotics are the sole reason for my wellness:

I generally feel better on probiotics, but maybe it's because when I'm well enough to remember to take probiotics, I'm also doing other good things for my health (exercise, eating healthy, meditation, other supplements, the universe aligning in such a fashion that my brain has just decided on its own to be less depressed).

It's not cheap, but I use this product.

This is a bit dense but if you want a summary of actual evidence, including some strains, it's helpful.

do you have some money to spend? SAM-e is a pretty safe supplement and starts working within two weeks. any kind that comes in a blister pack works. drs best is usually good value for the price https://www.amazon.com/Doctors-Best-Support-Enteric-Tablets/dp/B0011FTJZ0 take one in the morning and one before lunch, on an empty stomach. if you tolerate it well increase to 2 per dose, if you get stomach upset, back down


EDIT: don't take it if you are on SSRIs or are bipolar

There are some great books out on this stuff.

The Power of Habit: The Power of Habit: Why We Do What We Do in Life and Business https://www.amazon.com/dp/081298160X/ref=cm_sw_r_cp_api_i_Uk-WCbESHTEER

Atomic Habits: Atomic Habits: An Easy & Proven Way to Build Good Habits & Break Bad Ones https://www.amazon.com/dp/0735211299/ref=cm_sw_r_cp_api_i_Xl-

https://youtu.be/szgoDIkimNU

https://youtu.be/U_nzqnXWvSo

Light therapy has definitely helped me. I had SAD cycles as far back as middle school, but didn't know what was going on until halfway through college. Thankfully a therapist noticed the pattern and suggested a light box. I use it year round now, and turn it on as soon as my alarm goes off in the morning.

I'd also highly suggest policing your blue light exposure in the evening. That's the other side of the coin that people often ignore. We're exposed to so much artificial blue light from screens. The blue light tricks our brain into thinking it's daylight and screws up our production of melatonin and thus our sleep cycle. Your sleep cycle absolutely affects your physical and mental health. I use glasses like this at night when I'm watching TV or using my phone. I feel like limiting my light exposure has helped as much or more than the light box. The two approaches certainly support each other.

I liked Paxil (paroxetine). It is the most potent SSRI. I think I even took it with bupropion for a while. Why did I stop Paxil? I developed flat affect.

Alas, I've never found an SSRI, TCA, atypical, or MAOI that has much effect on dopamine.

Let me direct you at this point over to r/Anhedonia_Recovery to read my comment on this post - Pramipexole (Mirapex) For Anhedonia And Treatment-Resistant Depression: Guidelines, Studies, And Success Stories..

The drugs that have effects on dopamine agonism are pramipexole (Mirapex) and ropinirole (Requip). Of the two, pramipexole looks more promising for depression (and anhedonia). Pramipexole is primarily a D3 agonist, with some D2 and D4 agonism. Pramipexole is primarily a Parkinson's drug; ropinirole is for restless leg syndrome.

Anyhow, I think you may be overthinking things a bit, like the other commenter suggested. It may be that "Drug X" looks great on paper, but if you take it and it makes you nauseous, you won't like it. The clinical experience of your psychiatrist is also important for figuring out the right treatment for you.

Otherwise, get a copy of Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications 4th Edition by Stephen M. Stahl. I think you'll like it. You can reference some of it online at Stahl Online.

Most religions have developed to explain why we live and to deal with the problem that we are eventually going to die. I just finished a fascinating book called "Why God Won't Go Away: Brain Science and the Biology of Belief." Why God Won't Go Away: Brain Science and the Biology of Belief
https://www.amazon.com/dp/034544034X/ref=cm_sw_r_cp_apa_i_3aXqDbYSYK8J3

It explains the functions of the brain in layman's terms and shows that we have an evolved physical process for experiencing the "mystical" world. Basically, our brains have the ability to get a taste of dimensions beyond what we know as space and time. Most who have experienced this believe that it points to a higher being/unity/God/realm.

Personally, having a belief in something greater than myself has driven me to care more about my life on Earth. We may never understand why we live while we're living, but I have hope that after death I will.

Didn't help me, I bought https://www.amazon.com/gp/product/B0009MFUWC/ref=oh_aui_search_detailpage?ie=UTF8&th=1 and found it to be ineffective.

Sunlight works however, honestly even being outside on a cloudy day works. I was very disappointed after having high hopes with that lamp. Then again everyone is different and YMMV

Mad in America I think very big.

Prolab Caffeine Tablets, 100-Count https://www.amazon.com/dp/B0011865IQ?ref=yo_pop_ma_swf

Always with food, never extra doses. And of course check with your doctor if you’re instructed to limit caffeine intake

If you get PS, get it conjugated to DHA, DHA increases its uptake into neurons. The DHA also becomes more bioavailable itself. https://www.amazon.com/Country-Life-Sharp-Thought-Supports/dp/B000MES34O. Also for ALCAR there is a new option- ALCAR Arginate that is four times more potent at increasing NGF per weight.

No problem! If you’re interested in looking over some of the material beforehand, you could check out this book. It’s the skills worksheet book for DBT by Marsha Linehan, who invented DBT

You should look into somatoform disorders. I highly recommended you read Healing Back Pain by Dr. John E. Sarno.

http://www.amazon.com/Healing-Back-Pain-Mind-Body-Connection/dp/0446557684

First, understand that if you're worried about things they talk about in the media, you're being emotionally manipulated. You're being ginned up to feel scared and angry to increase their ratings.

Here's the cure that I guarantee you won't take: read the other side. For example, read this:

https://www.amazon.ca/Moral-Case-Fossil-Fuels/dp/1591847443

(you won't).